Covid-19 muaj cov txheej txheem spinous (s) protein, membrane (m) protein thiab Nucleocapsid (n) protein. Yuav kom tau txais kev kho mob zoo, covid-19 kev kuaj mob sai yog qhov tseem ceeb heev. Kev txheeb xyuas sai tuaj yeem txo qhov ntev ntawm kev nyob hauv tsev kho mob, txo kev siv tshuaj tiv thaiv kab mob thiab txo tus nqi hauv tsev kho mob, uas txuag tau nyiaj ntau. Covid-19 IgM & IgG kuaj cov khoom siv (immunochromatography) muab qhov yooj yim thiab ceev nrooj ntawm cov tshuaj tiv thaiv IgM & IgG hauv tib neeg cov ntshav. Vim nws qhov yooj yim thiab nrawm, nws yog qhov tsim nyog rau kev kho mob thaum ntxov thiab txhim kho kev ua haujlwm.
[kev soj ntsuam txoj cai]
Covid-19 IgM & IgG nrhiav pom reagent (tom qab no hu ua covid-19 daim npav kuaj pom) siv lub hauv paus ntsiab lus ntawm antigen antibody tshwj xeeb khi thiab immunochromatographic technology, Cov reagent muaj cov tshuaj tiv thaiv tib neeg IgM monoclonal antibody (m) thiab tshuaj tiv thaiv tib neeg IgG monoclonal antibody (g) ua ntej tsau rau ntawm qhov chaw kuaj (c) ntawm lub xeem strip, Tshis los tiv thaiv qaib IgY hauv cheeb tsam tswj kom zoo, tiv thaiv covid-19 IgM tshwj xeeb protein ua ke colloidal kub (m.nc-gc kub txheem conjugate) ua ntej tsau rau ntawm lub conjugate tso tawm ncoo thiab nqaij qaib IgY txuas colloidal kub. Thaum lub sij hawm kuaj, tso cov qauv mus rau hauv lub reagent loading qhov (s). Cov qauv txav mus rau qhov kuaj pom kab los ntawm capillary chromatography. Yog tias muaj IgM cov tshuaj tiv thaiv kab mob tiv thaiv covid-19 hauv cov qauv, nws yuav ua ke nrog m.nc-gc kub qauv conjugate los ua igm-m.nc-gc complex. Qhov kev ua haujlwm no txuas ntxiv mus rau pem hauv ntej raws li kev ua ntawm chromatography thiab raug ntes los ntawm kev tiv thaiv tib neeg IgM monoclonal antibody yav dhau los kho rau M kab los tsim ib pawg liab caw, qhia tias IgM zoo ntawm covid-19; Yog tias muaj IgG cov tshuaj tiv thaiv kab mob tiv thaiv covid-19 hauv cov qauv uas yuav tsum tau kuaj, nyob rau hauv qhov kev txiav txim ntawm capillary chromatography, nws kuj khi rau m.nc-gc thiab raug ntes los ntawm g kab los tsim ib lub caw liab, qhia tias covid-19 IgG yog qhov zoo; Yog tias M thiab / lossis G tsis tsim xim, nws qhia tau tias tus qauv yog covid-19 tsis zoo; Covid-19 IgM & IgG kuaj pom reagent muaj cov kab tswj tau zoo. Seb puas muaj IgM & IgG nyob rau hauv cov qauv los yog tsis, ib tug caw liab band yuav tshwm nyob rau hauv lub zoo tswj cheeb tsam (c). Cov kab liab caw liab hauv thaj chaw tswj kom zoo (c) yog tus qauv los txiav txim seb puas muaj cov qauv txaus thiab seb cov txheej txheem chromatography puas zoo.